Dynamic Kinetic Resolution of Alcohols by Enantioselective Silylation Enabled by Two Orthogonal Transition‐Metal Catalysts

A nonenzymatic dynamic kinetic resolution of acyclic and cyclic benzylic alcohols is reported. The approach merges rapid transition‐metal‐catalyzed alcohol racemization and enantioselective Cu‐H‐catalyzed dehydrogenative Si‐O coupling of alcohols and hydrosilanes. The catalytic processes are orthogo...

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Detalles Bibliográficos
Autores principales: Seliger, Jan, Oestreich, Martin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Communications
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7821270/
https://www.ncbi.nlm.nih.gov/pubmed/33107692
http://dx.doi.org/10.1002/anie.202010484

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7821270/
https://www.ncbi.nlm.nih.gov/pubmed/33107692
http://dx.doi.org/10.1002/anie.202010484

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