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Population Pharmacokinetic Analysis for Plasma and Epithelial Lining Fluid Ceftolozane/Tazobactam Concentrations in Patients With Ventilated Nosocomial Pneumonia

Ceftolozane/tazobactam (C/T) is a combination of a novel cephalosporin with tazobactam, recently approved for the treatment of hospital‐acquired and ventilator‐associated pneumonia. The plasma pharmacokinetics (PK) of a 3‐g dose of C/T (2 g ceftolozane and 1 g tazobactam) administered via a 1‐hour i...

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Detalles Bibliográficos
Autores principales: Zhang, Zufei, Patel, Yogesh T., Fiedler‐Kelly, Jill, Feng, Hwa‐Ping, Bruno, Christopher J., Gao, Wei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7821292/
https://www.ncbi.nlm.nih.gov/pubmed/32949031
http://dx.doi.org/10.1002/jcph.1733