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Developmental and reproductive safety evaluation of AV7909 anthrax vaccine candidate in rats

The AV7909 vaccine, consists of the Anthrax Vaccine Adsorbed (AVA) bulk drug substance and the immunostimulatory Toll‐like receptor 9 agonist oligodeoxynucleotide adjuvant CPG 7909. The purpose of this research was to evaluate the potential maternal, reproductive, and developmental toxicity of AV790...

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Detalles Bibliográficos
Autores principales: Mylchreest, Eve, Smiley, M. Autumn, Ballin, Jeff D., Blauth, Bruna, Shearer, Jeffry, Reece, Joshua, Ionin, Boris, Savransky, Vladimir
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley & Sons, Inc. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7821328/
https://www.ncbi.nlm.nih.gov/pubmed/33067910
http://dx.doi.org/10.1002/bdr2.1815