MYBL2-Driven Transcriptional Programs Link Replication Stress and Error-prone DNA Repair With Genomic Instability in Lung Adenocarcinoma

It has long been recognized that defects in cell cycle checkpoint and DNA repair pathways give rise to genomic instability, tumor heterogeneity, and metastasis. Despite this knowledge, the transcription factor-mediated gene expression programs that enable survival and proliferation in the face of en...

Descripción completa

Detalles Bibliográficos
Autores principales: Morris, Benjamin B., Wages, Nolan A., Grant, Patrick A., Stukenberg, P. Todd, Gentzler, Ryan D., Hall, Richard D., Akerley, Wallace L., Varghese, Thomas K., Arnold, Susanne M., Williams, Terence M., Coppola, Vincenzo, Jones, David R., Auble, David T., Mayo, Marty W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Oncology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7821388/
https://www.ncbi.nlm.nih.gov/pubmed/33489883
http://dx.doi.org/10.3389/fonc.2020.585551

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7821388/
https://www.ncbi.nlm.nih.gov/pubmed/33489883
http://dx.doi.org/10.3389/fonc.2020.585551

Ejemplares similares