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SOX4 maintains the stemness of cancer cells via transcriptionally enhancing HDAC1 revealed by comparative proteomics study

BACKGROUND: Cancer stem cells (CSCs) are the root of human cancer development and the major cause of treatment failure. Aberrant elevation of SOX4, a member of SOX (SRY-related HMG-box) family transcription factors, has been identified in many types of human cancer and promotes cancer development. H...

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Detalles Bibliográficos
Autores principales: Liu, Jingshu, Qiu, Jiangfeng, Zhang, Zhiqi, Zhou, Lei, Li, Yunzhe, Ding, Dongyan, Zhang, Yang, Zou, Dongling, Wang, Dong, Zhou, Qi, Lang, Tingyuan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7821488/
https://www.ncbi.nlm.nih.gov/pubmed/33482915
http://dx.doi.org/10.1186/s13578-021-00539-y