RTA‐408 protects against propofol‐induced cognitive impairment in neonatal mice via the activation of Nrf2 and the inhibition of NF‐κB p65 nuclear translocation

OBJECTIVE: To explore the effect of RTA‐408 on the propofol‐induced cognitive impairment of neonatal mice via regulating Nrf2 and NF‐κB p65 nuclear translocation. METHODS: C57BL/6 neonatal mice were randomized into intralipid, propofol, vehicle + propofol, and RTA‐408 + propofol groups. The learning...

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Detalles Bibliográficos
Autores principales: Zhang, Ling, Zhou, Qian, Zhou, Chun‐Li
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7821557/
https://www.ncbi.nlm.nih.gov/pubmed/33295701
http://dx.doi.org/10.1002/brb3.1918

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7821557/
https://www.ncbi.nlm.nih.gov/pubmed/33295701
http://dx.doi.org/10.1002/brb3.1918

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