Shear stress associated with cardiopulmonary bypass induces expression of inflammatory cytokines and necroptosis in monocytes

Cardiopulmonary bypass (CPB) is required during most cardiac surgeries. CBP drives systemic inflammation and multiorgan dysfunction that is especially severe in neonatal patients. Limited understanding of molecular mechanisms underlying CPB-associated inflammation presents a significant barrier to i...

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Detalles Bibliográficos
Autores principales: Tu, Lan N., Hsieh, Lance, Kajimoto, Masaki, Charette, Kevin, Kibiryeva, Nataliya, Forero, Adriana, Hampson, Sarah, Marshall, Jennifer A., O’Brien, James, Scatena, Marta, Portman, Michael A., Savan, Ram, Benner, Chris, Aliseda, Alberto, Nuri, Muhammad, Bittel, Douglas, Pastuszko, Peter, Nigam, Vishal
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Clinical Investigation 2021
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7821587/
https://www.ncbi.nlm.nih.gov/pubmed/33232305
http://dx.doi.org/10.1172/jci.insight.141341

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7821587/
https://www.ncbi.nlm.nih.gov/pubmed/33232305
http://dx.doi.org/10.1172/jci.insight.141341

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