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Dissecting strategies to tune the therapeutic potential of SARS-CoV-2–specific monoclonal antibody CR3022

The rapid spread of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), coupled with a lack of therapeutics, has paralyzed the globe. Although significant effort has been invested in identifying antibodies that block infection, the ability of antibodies to target infected cells through Fc...

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Detalles Bibliográficos
Autores principales: Atyeo, Caroline, Slein, Matthew D., Fischinger, Stephanie, Burke, John, Schäfer, Alexandra, Leist, Sarah R., Kuzmina, Natalia A., Mire, Chad, Honko, Anna, Johnson, Rebecca, Storm, Nadia, Bernett, Matthew, Tong, Pei, Zuo, Teng, Lin, Junrui, Zuiani, Adam, Linde, Caitlyn, Suscovich, Todd, Wesemann, Duane R., Griffiths, Anthony, Desjarlais, John R., Juelg, Boris D., Goudsmit, Jaap, Bukreyev, Alexander, Baric, Ralph, Alter, Galit
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Clinical Investigation 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7821590/
https://www.ncbi.nlm.nih.gov/pubmed/33427208
http://dx.doi.org/10.1172/jci.insight.143129