Stem cell–derived CAR T cells traffic to HIV reservoirs in macaques

Allogeneic hematopoietic stem cell transplantation (allo-HSCT) with CCR5(–) donor cells is the only treatment known to cure HIV-1 in patients with underlying malignancy. This is likely due to a donor cell–mediated graft-versus-host effect targeting HIV reservoirs. Allo-HSCT would not be an acceptabl...

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Detalles Bibliográficos
Autores principales: Barber-Axthelm, Isaac M., Barber-Axthelm, Valerie, Sze, Kai Yin, Zhen, Anjie, Suryawanshi, Gajendra W., Chen, Irvin S.Y., Zack, Jerome A., Kitchen, Scott G., Kiem, Hans-Peter, Peterson, Christopher W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Clinical Investigation 2021
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7821595/
https://www.ncbi.nlm.nih.gov/pubmed/33427210
http://dx.doi.org/10.1172/jci.insight.141502

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7821595/
https://www.ncbi.nlm.nih.gov/pubmed/33427210
http://dx.doi.org/10.1172/jci.insight.141502

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