Timing of proteasome inhibition as a pharmacologic strategy for prevention of muscle contractures in neonatal brachial plexus injury

Neonatal brachial plexus injury (NBPI) causes disabling and incurable contractures, or limb stiffness, which result from proteasome‐mediated protein degradation impairing the longitudinal growth of neonatally denervated muscles. We recently showed in a mouse model that the 20S proteasome inhibitor,...

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Detalles Bibliográficos
Autores principales: Goh, Qingnian, Nikolaou, Sia, Shay‐Winkler, Kritton, Emmert, Marianne E., Cornwall, Roger
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7821701/
https://www.ncbi.nlm.nih.gov/pubmed/33236396
http://dx.doi.org/10.1096/fj.202002194

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7821701/
https://www.ncbi.nlm.nih.gov/pubmed/33236396
http://dx.doi.org/10.1096/fj.202002194

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