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Partial Protection From Lupus-Like Disease by B-Cell Specific Type I Interferon Receptor Deficiency

Systemic lupus erythematosus (SLE) is an autoimmune disease that can present with many different permutations of symptom presentation. A large subset of SLE patients have been shown to present with elevated interferon stimulated gene (ISG) expression, and Type I IFNs (IFNαβ) have been shown to drive...

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Detalles Bibliográficos
Autores principales: Keller, Emma J., Patel, Neeva B., Patt, Madeline, Nguyen, Jane K., Jørgensen, Trine N.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7821742/
https://www.ncbi.nlm.nih.gov/pubmed/33488628
http://dx.doi.org/10.3389/fimmu.2020.616064