Cargando…

Blocking pro-inflammatory platelet-activating factor receptors and activating cell survival pathways: A novel therapeutic strategy in experimental ischemic stroke

OBJECTIVE: Acute ischemic stroke triggers complex neurovascular, neuroinflammatory, and synaptic alterations. This study explores whether blocking pro-inflammatory platelet-activating factor receptor (PAF-R) plus selected docosanoids after middle cerebral artery occlusion (MCAo) would lead to neurol...

Descripción completa

Detalles Bibliográficos
Autores principales: Belayev, Ludmila, Obenaus, Andre, Mukherjee, Pranab K., Knott, Eric J., Khoutorova, Larissa, Reid, Madigan M., Roque, Cassia R., Nguyen, Lawrence, Lee, Jeong Bin, Petasis, Nicos A., Oria, Reinaldo B., Bazan, Nicolas G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Wolters Kluwer - Medknow 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7821809/
https://www.ncbi.nlm.nih.gov/pubmed/33506149
http://dx.doi.org/10.4103/bc.bc_36_20