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Blocking pro-inflammatory platelet-activating factor receptors and activating cell survival pathways: A novel therapeutic strategy in experimental ischemic stroke
OBJECTIVE: Acute ischemic stroke triggers complex neurovascular, neuroinflammatory, and synaptic alterations. This study explores whether blocking pro-inflammatory platelet-activating factor receptor (PAF-R) plus selected docosanoids after middle cerebral artery occlusion (MCAo) would lead to neurol...
Autores principales: | Belayev, Ludmila, Obenaus, Andre, Mukherjee, Pranab K., Knott, Eric J., Khoutorova, Larissa, Reid, Madigan M., Roque, Cassia R., Nguyen, Lawrence, Lee, Jeong Bin, Petasis, Nicos A., Oria, Reinaldo B., Bazan, Nicolas G. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Wolters Kluwer - Medknow
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7821809/ https://www.ncbi.nlm.nih.gov/pubmed/33506149 http://dx.doi.org/10.4103/bc.bc_36_20 |
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