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Modulation of microglia activation and Alzheimer's disease: CX3 chemokine ligand 1/CX3CR and P2X(7)R signaling

Alzheimer's disease (AD) is a progressive neurodegenerative disease characterized by cognitive deficits. Two hallmarks of AD that cause chronic inflammation and lead to neuronal dysfunction and damage are tau tangles and amyloid plaques. Microglial cells, the primary immune cells of the central...

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Detalles Bibliográficos
Autores principales: Suresh, Pavithra, Phasuk, Sarayut, Liu, Ingrid Y.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Wolters Kluwer - Medknow 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7821819/
https://www.ncbi.nlm.nih.gov/pubmed/33505871
http://dx.doi.org/10.4103/tcmj.tcmj_144_20