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Noninvasive characterization of Alzheimer’s disease by circulating, cell-free messenger RNA next-generation sequencing

The lack of accessible noninvasive tools to examine the molecular alterations occurring in the brain limits our understanding of the causes and progression of Alzheimer’s disease (AD), as well as the identification of effective therapeutic strategies. Here, we conducted a comprehensive profiling of...

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Detalles Bibliográficos
Autores principales: Toden, Shusuke, Zhuang, Jiali, Acosta, Alexander D., Karns, Amy P., Salathia, Neeraj S., Brewer, James B., Wilcock, Donna M., Aballi, Jonathan, Nerenberg, Mike, Quake, Stephen R., Ibarra, Arkaitz
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for the Advancement of Science 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7821903/
https://www.ncbi.nlm.nih.gov/pubmed/33298436
http://dx.doi.org/10.1126/sciadv.abb1654