Cargando…

The chaperonin CCT controls T cell receptor–driven 3D configuration of centrioles

T lymphocyte activation requires the formation of immune synapses (IS) with antigen-presenting cells. The dynamics of membrane receptors, signaling scaffolds, microfilaments, and microtubules at the IS determine the potency of T cell activation and subsequent immune response. Here, we show that the...

Descripción completa

Detalles Bibliográficos
Autores principales: Martin-Cofreces, N. B., Chichon, F. J., Calvo, E., Torralba, D., Bustos-Moran, E., Dosil, S. G., Rojas-Gomez, A., Bonzon-Kulichenko, E., Lopez, J. A., Otón, J., Sorrentino, A., Zabala, J. C., Vernos, I., Vazquez, J., Valpuesta, J. M., Sanchez-Madrid, F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for the Advancement of Science 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7821906/
https://www.ncbi.nlm.nih.gov/pubmed/33268369
http://dx.doi.org/10.1126/sciadv.abb7242