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The chaperonin CCT controls T cell receptor–driven 3D configuration of centrioles
T lymphocyte activation requires the formation of immune synapses (IS) with antigen-presenting cells. The dynamics of membrane receptors, signaling scaffolds, microfilaments, and microtubules at the IS determine the potency of T cell activation and subsequent immune response. Here, we show that the...
Autores principales: | Martin-Cofreces, N. B., Chichon, F. J., Calvo, E., Torralba, D., Bustos-Moran, E., Dosil, S. G., Rojas-Gomez, A., Bonzon-Kulichenko, E., Lopez, J. A., Otón, J., Sorrentino, A., Zabala, J. C., Vernos, I., Vazquez, J., Valpuesta, J. M., Sanchez-Madrid, F. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Association for the Advancement of Science
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7821906/ https://www.ncbi.nlm.nih.gov/pubmed/33268369 http://dx.doi.org/10.1126/sciadv.abb7242 |
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