Nanoparticles Based on Quaternary Ammonium Chitosan-methyl-β-cyclodextrin Conjugate for the Neuropeptide Dalargin Delivery to the Central Nervous System: An In Vitro Study

Peptide oral administration is a hard goal to reach, especially if the brain is the target site. The purpose of the present study was to set up a vehicle apt to promote oral absorption of the neuropeptide dalargin (DAL), allowing it to cross the intestinal mucosal barrier, resist enzymatic degradati...

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Detalles Bibliográficos
Autores principales: Migone, Chiara, Mattii, Letizia, Giannasi, Martina, Moscato, Stefania, Cesari, Andrea, Zambito, Ylenia, Piras, Anna Maria
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7822029/
https://www.ncbi.nlm.nih.gov/pubmed/33374997
http://dx.doi.org/10.3390/pharmaceutics13010005

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7822029/
https://www.ncbi.nlm.nih.gov/pubmed/33374997
http://dx.doi.org/10.3390/pharmaceutics13010005

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