Insights into the Membranolytic Activity of Antimalarial Drug-Cell Penetrating Peptide Conjugates

Conjugation of TP10, a cell-penetrating peptide with intrinsic antimalarial activity, to the well-known antimalarial drugs chloroquine and primaquine has been previously shown to enhance the peptide’s action against, respectively, blood- and liver-stage malaria parasites. Yet, this was achieved at t...

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Detalles Bibliográficos
Autores principales: Aguiar, Luísa, Pinheiro, Marina, Neves, Ana Rute, Vale, Nuno, Defaus, Sira, Andreu, David, Reis, Salette, Gomes, Paula
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7822033/
https://www.ncbi.nlm.nih.gov/pubmed/33375073
http://dx.doi.org/10.3390/membranes11010004

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7822033/
https://www.ncbi.nlm.nih.gov/pubmed/33375073
http://dx.doi.org/10.3390/membranes11010004

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