Analogues of 2′-hydroxychalcone with modified C4-substituents as the inhibitors against human acetylcholinesterase

A series of C4-substituted tertiary nitrogen-bearing 2′-hydroxychalcones were designed and synthesised based on a previous mixed type acetylcholinesterase inhibitor. Majority of the 2′-hydroxychalcone analogues displayed a better inhibition against acetylcholinesterase (AChE) than butyrylcholinester...

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Detalles Bibliográficos
Autores principales: Sukumaran, Sri Devi, Nasir, Shah Bakhtiar, Tee, Jia Ti, Buckle, Michael J. C., Othman, Rozana, Rahman, Noorsaadah Abd., Lee, Vannajan Sanghiran, Bukhari, Syed Nasir Abbas, Chee, Chin Fei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2020
Materias:
Short Communication
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7822063/
https://www.ncbi.nlm.nih.gov/pubmed/33243025
http://dx.doi.org/10.1080/14756366.2020.1847100

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7822063/
https://www.ncbi.nlm.nih.gov/pubmed/33243025
http://dx.doi.org/10.1080/14756366.2020.1847100

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