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Discovery of indole-3-butyric acid derivatives as potent histone deacetylase inhibitors

In discovery of HDAC inhibitors (HDACIs) with improved anticancer potency, structural modification was performed on the previous derived indole-3-butyric acid derivative. Among all the synthesised compounds, molecule I13 exhibited high HDAC inhibitory and antiproliferative potencies in the in vitro...

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Detalles Bibliográficos
Autores principales:	Chen, Yiming, Zhang, Lihui, Zhang, Lin, Jiang, Qixiao, Zhang, Lei
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Taylor & Francis 2021
Materias:	Research Paper
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7822065/ https://www.ncbi.nlm.nih.gov/pubmed/33445997 http://dx.doi.org/10.1080/14756366.2020.1870457

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