Inhibition of α-, β- and γ-carbonic anhydrases from the pathogenic bacterium Vibrio cholerae with aromatic sulphonamides and clinically licenced drugs – a joint docking/molecular dynamics study

The binding mode of aromatic sulphonamides and clinically licenced drugs to the three carbonic anhydrase (CA, EC 4.2.1.1) isoforms from the human pathogen V. cholerae was here thouroghly characterised by a joint docking and molecular dynamics in silico protocol. In fact, VchCA, VchCAβ, and VchCAγ ar...

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Detalles Bibliográficos
Autores principales: Bonardi, Alessandro, Nocentini, Alessio, Osman, Sameh Mohamed, Alasmary, Fatmah Ali, Almutairi, Tahani Mazyad, Abdullah, Dalal Saied, Gratteri, Paola, Supuran, Claudiu T.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2021
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7822066/
https://www.ncbi.nlm.nih.gov/pubmed/33472446
http://dx.doi.org/10.1080/14756366.2020.1862102

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7822066/
https://www.ncbi.nlm.nih.gov/pubmed/33472446
http://dx.doi.org/10.1080/14756366.2020.1862102

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