Targeting NPM1 in irradiated cells inhibits NPM1 binding to RAD51, RAD51 foci formation and radiosensitizes NSCLC

The ability of chemo-radiation therapy to control locally advanced stage III non-small cell lung cancer (NSCLC) is poor. While addition of consolidation immunotherapy has improved outcomes in subsets of patients there is still an urgent need for new therapeutic targets. Emerging research indicates t...

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Detalles Bibliográficos
Autores principales: Traver, Geri, Sekhar, Konjeti R., Crooks, Peter A., Keeney, Diane S., Freeman, Michael L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7822076/
https://www.ncbi.nlm.nih.gov/pubmed/33358698
http://dx.doi.org/10.1016/j.canlet.2020.12.023

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7822076/
https://www.ncbi.nlm.nih.gov/pubmed/33358698
http://dx.doi.org/10.1016/j.canlet.2020.12.023

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