APOE Variants in an Iberian Alzheimer Cohort Detected through an Optimized Sanger Sequencing Protocol

The primary genetic risk factor for late onset Alzheimer’s disease (LOAD) is the APOE4 allele of Apolipoprotein E (APOE) gene. The three most common variants of APOE are determined by single nucleotide polymorphisms (SNPs) rs429358 and rs7412. Our aim was to estimate allele and genotype frequencies...

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Detalles Bibliográficos
Autores principales: González, Ricardo D., Gomes, Iva, Gomes, Catarina, Rocha, Rita, Durães, Luís, Sousa, Patrícia, Figueruelo, Manuel, Rodríguez, Maria, Pita, Carmen, Hornero, Roberto, Gómez, Carlos, Lopes, Alexandra M., Pinto, Nádia, Martins, Sandra
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7822120/
https://www.ncbi.nlm.nih.gov/pubmed/33375167
http://dx.doi.org/10.3390/genes12010004

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7822120/
https://www.ncbi.nlm.nih.gov/pubmed/33375167
http://dx.doi.org/10.3390/genes12010004

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