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Acid Ceramidase Rescues Cystic Fibrosis Mice from Pulmonary Infections
Previous studies have shown that sphingosine kills a variety of pathogenic bacteria, including Pseudomonas aeruginosa and Staphylococcus aureus. Sphingosine concentrations are decreased in airway epithelial cells of cystic fibrosis (CF) mice, and this defect has been linked to the infection suscepti...
Autores principales: | , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Society for Microbiology
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7822142/ https://www.ncbi.nlm.nih.gov/pubmed/33139382 http://dx.doi.org/10.1128/IAI.00677-20 |