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Acid Ceramidase Rescues Cystic Fibrosis Mice from Pulmonary Infections

Previous studies have shown that sphingosine kills a variety of pathogenic bacteria, including Pseudomonas aeruginosa and Staphylococcus aureus. Sphingosine concentrations are decreased in airway epithelial cells of cystic fibrosis (CF) mice, and this defect has been linked to the infection suscepti...

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Detalles Bibliográficos
Autores principales:	Becker, Katrin Anne, Verhaegh, Rabea, Verhasselt, Hedda-Luise, Keitsch, Simone, Soddemann, Matthias, Wilker, Barbara, Wilson, Gregory C., Buer, Jan, Ahmad, Syed A., Edwards, Michael J., Gulbins, Erich
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Society for Microbiology 2021
Materias:	Cellular Microbiology: Pathogen-Host Cell Molecular Interactions
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7822142/ https://www.ncbi.nlm.nih.gov/pubmed/33139382 http://dx.doi.org/10.1128/IAI.00677-20

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