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High LARGE1 Expression May Predict Benefit from Adjuvant Chemotherapy in Resected Non-Small-Cell Lung Cancer

BACKGROUND: LARGE1 plays a pivotal role in glycosylation of alpha-Dystroglycan (α-DG) and is aberrantly downregulated in cell lines originating from epithelium-derived cancers including lung cancer. However, the expression of LARGE1 and its clinical significance in NSCLC are not clear. MATERIALS AND...

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Detalles Bibliográficos
Autores principales: Liu, Yu, Huang, Shirui, Kuang, Mengjiao, Wang, Huiyan, Xie, Qipeng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7822230/
https://www.ncbi.nlm.nih.gov/pubmed/33500650
http://dx.doi.org/10.2147/PGPM.S271516