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Serum Amyloid P inhibits single stranded RNA-induced lung inflammation, lung damage, and cytokine storm in mice

SARS-CoV-2 is a single stranded RNA (ssRNA) virus and contains GU-rich sequences distributed abundantly in the genome. In COVID-19, the infection and immune hyperactivation causes accumulation of inflammatory immune cells, blood clots, and protein aggregates in lung fluid, increased lung alveolar wa...

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Detalles Bibliográficos
Autores principales: Karhadkar, Tejas R., Pilling, Darrell, Gomer, Richard H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7822324/
https://www.ncbi.nlm.nih.gov/pubmed/33481950
http://dx.doi.org/10.1371/journal.pone.0245924