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Induced pluripotent stem cells derived from the developing striatum as a potential donor source for cell replacement therapy for Huntington disease

BACKGROUND: Cell replacement therapy (CRT) for Huntington disease (HD) requires a source of striatal (STR) progenitors capable of restoring the function lost due to STR degeneration. Authentic STR progenitors can be collected from the fetal putative striatum, or whole ganglionic eminence (WGE), but...

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Detalles Bibliográficos
Autores principales: Choompoo, Narawadee, Bartley, Oliver J.M., Precious, Sophie V., Vinh, Ngoc-nga, Schnell, Christian, Garcia, Ana, Roberton, Victoria H., Williams, Nigel M., Kemp, Paul J., Kelly, Claire M., Rosser, Anne E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7822401/
https://www.ncbi.nlm.nih.gov/pubmed/33246883
http://dx.doi.org/10.1016/j.jcyt.2020.06.001