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Improved Bioavailability of Montelukast through a Novel Oral Mucoadhesive Film in Humans and Mice

The leukotriene receptor antagonist Montelukast (MTK) is an approved medication for the treatment of asthma and allergic rhinitis. The existing marketed tablet forms of MTK exhibit inconsistent uptake and bioavailability, which partially explains the presence of a significant proportion of MTK low-...

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Detalles Bibliográficos
Autores principales: Michael, Johanna, Bessa de Sousa, Diana, Conway, Justin, Gonzalez-Labrada, Erick, Obeid, Rodolphe, Tevini, Julia, Felder, Thomas, Hutter-Paier, Birgit, Zerbe, Horst, Paiement, Nadine, Aigner, Ludwig
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7822410/
https://www.ncbi.nlm.nih.gov/pubmed/33374646
http://dx.doi.org/10.3390/pharmaceutics13010012