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Improved Bioavailability of Montelukast through a Novel Oral Mucoadhesive Film in Humans and Mice
The leukotriene receptor antagonist Montelukast (MTK) is an approved medication for the treatment of asthma and allergic rhinitis. The existing marketed tablet forms of MTK exhibit inconsistent uptake and bioavailability, which partially explains the presence of a significant proportion of MTK low-...
Autores principales: | Michael, Johanna, Bessa de Sousa, Diana, Conway, Justin, Gonzalez-Labrada, Erick, Obeid, Rodolphe, Tevini, Julia, Felder, Thomas, Hutter-Paier, Birgit, Zerbe, Horst, Paiement, Nadine, Aigner, Ludwig |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7822410/ https://www.ncbi.nlm.nih.gov/pubmed/33374646 http://dx.doi.org/10.3390/pharmaceutics13010012 |
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