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Pharmacokinetics of Mephedrone Enantiomers in Whole Blood after a Controlled Intranasal Administration to Healthy Human Volunteers

Mephedrone, which is one of the most popular synthetic cathinones, has one chiral centre and thus exists as two enantiomers: R-(+)-mephedrone and S-(−)-mephedrone. There are some preliminary data suggesting that the enantiomers of mephedrone may display enantioselective pharmacokinetics and exhibit...

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Detalles Bibliográficos
Autores principales: Czerwinska, Joanna, Parkin, Mark C., Cilibrizzi, Agostino, George, Claire, Kicman, Andrew T., Dargan, Paul I., Abbate, Vincenzo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7822411/
https://www.ncbi.nlm.nih.gov/pubmed/33374623
http://dx.doi.org/10.3390/ph14010005