Phenoxyalkylimidazoles with an oxadiazole moiety are subject to efflux in Mycobacterium tuberculosis

The phenoxyalkylimidazoles (PAI) are an attractive chemical series with potent anti-tubercular activity targeting Mycobacterium tuberculosis respiration. Our aim was to determine if the PAI compounds are subject to efflux. Two analogs containing an oxadiazole had improved potency in the presence of...

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Detalles Bibliográficos
Autores principales: Thayer, Mai B., Parish, Tanya
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2021
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7822546/
https://www.ncbi.nlm.nih.gov/pubmed/33481781
http://dx.doi.org/10.1371/journal.pone.0239353

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7822546/
https://www.ncbi.nlm.nih.gov/pubmed/33481781
http://dx.doi.org/10.1371/journal.pone.0239353

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