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Rutaecarpine Ameliorates Pressure Overload Cardiac Hypertrophy by Suppression of Calcineurin and Angiotensin II

Cardiac hypertrophy is a major pathological process to result in heart failure and sudden death. Rutaecarpine, a pentacyclic indolopyridoquinazolinone alkaloid extracted from Evodia rutaecarpa with multiple pharmacological activities, yet the underlying protective effects and the mechanisms on cardi...

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Detalles Bibliográficos
Autores principales: Li, Shujun, Huang, Bo, Zhou, Changfei, Shi, Jingshan, Wu, Qin, Jiang, Qingsong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7822676/
https://www.ncbi.nlm.nih.gov/pubmed/33510809
http://dx.doi.org/10.1155/2021/8857329