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Mobility of Lower MA-Helices for Ion Conduction through Lateral Portals in 5-HT(3A) Receptors
The intracellular domain of the serotonin type 3A receptor, a pentameric ligand-gated ion channel, is crucial for regulating conductance. Ion permeation through the extracellular vestibule and the transmembrane channel is well understood, whereas the specific ion conduction pathway through the intra...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The Biophysical Society
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7822733/ https://www.ncbi.nlm.nih.gov/pubmed/33157122 http://dx.doi.org/10.1016/j.bpj.2020.10.029 |