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Mobility of Lower MA-Helices for Ion Conduction through Lateral Portals in 5-HT(3A) Receptors

The intracellular domain of the serotonin type 3A receptor, a pentameric ligand-gated ion channel, is crucial for regulating conductance. Ion permeation through the extracellular vestibule and the transmembrane channel is well understood, whereas the specific ion conduction pathway through the intra...

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Detalles Bibliográficos
Autores principales: Stuebler, Antonia G., Jansen, Michaela
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Biophysical Society 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7822733/
https://www.ncbi.nlm.nih.gov/pubmed/33157122
http://dx.doi.org/10.1016/j.bpj.2020.10.029