Integrative computational approach identifies drug targets in CD4(+) T-cell-mediated immune disorders

CD4(+) T cells provide adaptive immunity against pathogens and abnormal cells, and they are also associated with various immune-related diseases. CD4(+) T cells’ metabolism is dysregulated in these pathologies and represents an opportunity for drug discovery and development. Genome-scale metabolic m...

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Detalles Bibliográficos
Autores principales: Puniya, Bhanwar Lal, Amin, Rada, Lichter, Bailee, Moore, Robert, Ciurej, Alex, Bennett, Sydney J., Shah, Ab Rauf, Barberis, Matteo, Helikar, Tomáš
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7822845/
https://www.ncbi.nlm.nih.gov/pubmed/33483502
http://dx.doi.org/10.1038/s41540-020-00165-3

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7822845/
https://www.ncbi.nlm.nih.gov/pubmed/33483502
http://dx.doi.org/10.1038/s41540-020-00165-3

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