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Molecular pathology associated with altered synaptic transcriptome in the dorsolateral prefrontal cortex of depressed subjects

Disrupted synaptic plasticity is the hallmark of major depressive disorder (MDD), with accompanying changes at the molecular and cellular levels. Often, the maladaptive molecular changes at the synapse are the result of global transcriptional reprogramming dictated by activity-dependent synaptic mod...

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Detalles Bibliográficos
Autores principales: Yoshino, Yuta, Roy, Bhaskar, Kumar, Nilesh, Shahid Mukhtar, M., Dwivedi, Yogesh
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7822869/
https://www.ncbi.nlm.nih.gov/pubmed/33483466
http://dx.doi.org/10.1038/s41398-020-01159-9