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Molecular pathology associated with altered synaptic transcriptome in the dorsolateral prefrontal cortex of depressed subjects
Disrupted synaptic plasticity is the hallmark of major depressive disorder (MDD), with accompanying changes at the molecular and cellular levels. Often, the maladaptive molecular changes at the synapse are the result of global transcriptional reprogramming dictated by activity-dependent synaptic mod...
Autores principales: | Yoshino, Yuta, Roy, Bhaskar, Kumar, Nilesh, Shahid Mukhtar, M., Dwivedi, Yogesh |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7822869/ https://www.ncbi.nlm.nih.gov/pubmed/33483466 http://dx.doi.org/10.1038/s41398-020-01159-9 |
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