Essential role for autophagy protein VMP1 in maintaining neuronal homeostasis and preventing axonal degeneration

Vacuole membrane protein 1 (VMP1), the endoplasmic reticulum (ER)-localized autophagy protein, plays a key role during the autophagy process in mammalian cells. To study the impact of VMP1-deficiency on midbrain dopaminergic (mDAergic) neurons, we selectively deleted VMP1 in the mDAergic neurons of...

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Detalles Bibliográficos
Autores principales: Wang, Panpan, Chen, Xi, Wang, Yuanyuan, Jia, Congcong, Liu, Xinyao, Wang, Ying, Wu, Haifeng, Cai, Huaibin, Shen, Han-Ming, Le, Weidong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7822891/
https://www.ncbi.nlm.nih.gov/pubmed/33483473
http://dx.doi.org/10.1038/s41419-021-03412-5

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7822891/
https://www.ncbi.nlm.nih.gov/pubmed/33483473
http://dx.doi.org/10.1038/s41419-021-03412-5

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