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Essential role for autophagy protein VMP1 in maintaining neuronal homeostasis and preventing axonal degeneration
Vacuole membrane protein 1 (VMP1), the endoplasmic reticulum (ER)-localized autophagy protein, plays a key role during the autophagy process in mammalian cells. To study the impact of VMP1-deficiency on midbrain dopaminergic (mDAergic) neurons, we selectively deleted VMP1 in the mDAergic neurons of...
Autores principales: | Wang, Panpan, Chen, Xi, Wang, Yuanyuan, Jia, Congcong, Liu, Xinyao, Wang, Ying, Wu, Haifeng, Cai, Huaibin, Shen, Han-Ming, Le, Weidong |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7822891/ https://www.ncbi.nlm.nih.gov/pubmed/33483473 http://dx.doi.org/10.1038/s41419-021-03412-5 |
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