CRISPR technologies and the search for the PAM-free nuclease

The ever-expanding set of CRISPR technologies and their programmable RNA-guided nucleases exhibit remarkable flexibility in DNA targeting. However, this flexibility comes with an ever-present constraint: the requirement for a protospacer adjacent motif (PAM) flanking each target. While PAMs play an...

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Detalles Bibliográficos
Autores principales: Collias, Daphne, Beisel, Chase L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Review Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7822910/
https://www.ncbi.nlm.nih.gov/pubmed/33483498
http://dx.doi.org/10.1038/s41467-020-20633-y

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7822910/
https://www.ncbi.nlm.nih.gov/pubmed/33483498
http://dx.doi.org/10.1038/s41467-020-20633-y

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