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Profiling serum antibodies with a pan allergen phage library identifies key wheat allergy epitopes

Allergic reactions occur when IgE molecules become crosslinked by antigens such as food proteins. Here we create the ‘AllerScan’ programmable phage display system to characterize the binding specificities of anti-allergen IgG and IgE antibodies in serum against thousands of allergenic proteins from...

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Detalles Bibliográficos
Autores principales: Monaco, Daniel R., Sie, Brandon M., Nirschl, Thomas R., Knight, Audrey C., Sampson, Hugh A., Nowak-Wegrzyn, Anna, Wood, Robert A., Hamilton, Robert G., Frischmeyer-Guerrerio, Pamela A., Larman, H. Benjamin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7822912/
https://www.ncbi.nlm.nih.gov/pubmed/33483508
http://dx.doi.org/10.1038/s41467-020-20622-1