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Profiling serum antibodies with a pan allergen phage library identifies key wheat allergy epitopes
Allergic reactions occur when IgE molecules become crosslinked by antigens such as food proteins. Here we create the ‘AllerScan’ programmable phage display system to characterize the binding specificities of anti-allergen IgG and IgE antibodies in serum against thousands of allergenic proteins from...
Autores principales: | Monaco, Daniel R., Sie, Brandon M., Nirschl, Thomas R., Knight, Audrey C., Sampson, Hugh A., Nowak-Wegrzyn, Anna, Wood, Robert A., Hamilton, Robert G., Frischmeyer-Guerrerio, Pamela A., Larman, H. Benjamin |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7822912/ https://www.ncbi.nlm.nih.gov/pubmed/33483508 http://dx.doi.org/10.1038/s41467-020-20622-1 |
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