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The HSP GRP94 interacts with macrophage intracellular complement C3 and impacts M2 profile during ER stress

The role of GRP94, an endoplasmic reticulum (ER) stress protein with both pro- and anti-inflammatory functions, has not been investigated in macrophages during ER stress, whereas ER stress has been reported in many diseases involving macrophages. In this work, we studied GRP94 in M1/LPS + IFNγ and M...

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Detalles Bibliográficos
Autores principales: Chaumonnot, Killian, Masson, Sophie, Sikner, Hugo, Bouchard, Alexanne, Baverel, Valentin, Bellaye, Pierre-Simon, Collin, Bertrand, Garrido, Carmen, Kohli, Evelyne
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7822929/
https://www.ncbi.nlm.nih.gov/pubmed/33483465
http://dx.doi.org/10.1038/s41419-020-03288-x