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Deubiquitylating enzymes in neuronal health and disease

Ubiquitylation and deubiquitylation play a pivotal role in protein homeostasis (proteostasis). Proteostasis shapes the proteome landscape in the human brain and its impairment is linked to neurodevelopmental and neurodegenerative disorders. Here we discuss the emerging roles of deubiquitylating enzy...

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Detalles Bibliográficos
Autores principales: Amer-Sarsour, Fatima, Kordonsky, Alina, Berdichevsky, Yevgeny, Prag, Gali, Ashkenazi, Avraham
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7822931/
https://www.ncbi.nlm.nih.gov/pubmed/33483467
http://dx.doi.org/10.1038/s41419-020-03361-5