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A theoretical and generalized approach for the assessment of the sample-specific limit of detection for clinical metagenomics
Metagenomics is a powerful tool to identify novel or unexpected pathogens, since it is generic and relatively unbiased. The limit of detection (LOD) is a critical parameter for the routine application of methods in the clinical diagnostic context. Although attempts for the determination of LODs for...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Research Network of Computational and Structural Biotechnology
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7822954/ https://www.ncbi.nlm.nih.gov/pubmed/33552445 http://dx.doi.org/10.1016/j.csbj.2020.12.040 |