Mitochondria–lysosome membrane contacts are defective in GDAP1-related Charcot–Marie–Tooth disease

Mutations in the GDAP1 gene cause Charcot–Marie–Tooth (CMT) neuropathy. GDAP1 is an atypical glutathione S-transferase (GST) of the outer mitochondrial membrane and the mitochondrial membrane contacts with the endoplasmic reticulum (MAMs). Here, we investigate the role of this GST in the autophagic...

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Detalles Bibliográficos
Autores principales: Cantarero, Lara, Juárez-Escoto, Elena, Civera-Tregón, Azahara, Rodríguez-Sanz, María, Roldán, Mónica, Benítez, Raúl, Hoenicka, Janet, Palau, Francesc
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2020
Materias:
General Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7823109/
https://www.ncbi.nlm.nih.gov/pubmed/33372681
http://dx.doi.org/10.1093/hmg/ddaa243

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7823109/
https://www.ncbi.nlm.nih.gov/pubmed/33372681
http://dx.doi.org/10.1093/hmg/ddaa243

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