Ultrasound‐microbubble cavitation facilitates adeno‐associated virus mediated cochlear gene transfection across the round‐window membrane

The round window of the cochlea provides an ideal route for delivering medicines and gene therapy reagents that can cross the round window membrane (RWM) into the inner ear. Recombinant adeno‐associated viruses (rAAVs) have several advantages and are recommended as viral vectors for gene transfectio...

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Detalles Bibliográficos
Autores principales: Zhang, Zhen, Chen, Zhengnong, Fan, Liqiang, Landry, Thomas, Brown, Jeremy, Yu, Zhiping, Yin, Shankai, Wang, Jian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley & Sons, Inc. 2020
Materias:
Research Reports
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7823126/
https://www.ncbi.nlm.nih.gov/pubmed/33532589
http://dx.doi.org/10.1002/btm2.10189

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7823126/
https://www.ncbi.nlm.nih.gov/pubmed/33532589
http://dx.doi.org/10.1002/btm2.10189

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