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Personalized‐induced neural stem cell therapy: Generation, transplant, and safety in a large animal model

In this study, we take an important step toward clinical translation by generating the first canine‐induced neural stem cells (iNSCs). We explore key aspects of scale‐up, persistence, and safety of personalized iNSC therapy in autologous canine surgery models. iNSCs are a promising new approach to t...

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Detalles Bibliográficos
Autores principales: Bomba, Hunter N., Sheets, Kevin T., Valdivia, Alain, Khagi, Simon, Ruterbories, Laura, Mariani, Christopher L., Borst, Luke B., Tokarz, Debra A., Hingtgen, Shawn D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley & Sons, Inc. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7823134/
https://www.ncbi.nlm.nih.gov/pubmed/33532581
http://dx.doi.org/10.1002/btm2.10171