Heterogeneity in clone dynamics within and adjacent to intestinal tumours identified by Dre-mediated lineage tracing

Somatic models of tissue pathology commonly use induction of gene-specific mutations in mice mediated by spatiotemporal regulation of Cre recombinase. Subsequent investigation of the onset and development of disease can be limited by the inability to track changing cellular behaviours over time. Her...

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Detalles Bibliográficos
Autores principales: Thorsen, Ann-Sofie, Khamis, Doran, Kemp, Richard, Colombé, Mathilde, Lourenço, Filipe C., Morrissey, Edward, Winton, Douglas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Company of Biologists Ltd 2021
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7823168/
https://www.ncbi.nlm.nih.gov/pubmed/33093165
http://dx.doi.org/10.1242/dmm.046706

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7823168/
https://www.ncbi.nlm.nih.gov/pubmed/33093165
http://dx.doi.org/10.1242/dmm.046706

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